Deutsch
Italiano
English
Welcome to Framagene
A few years ago genetical analysis were very time- and work-intensive. That's why they were restricted to a few molecular biology research laboratories.
In the last years the deployment of molecular biology analysis procedures revolutionized the medical diagnostics and the deployment of individual gene sequences has become more experienced.
The analysis are Single-Nucleotid-Polymorohisms (SNPs), i.e. in literature extensively described and analyzed variations of single base pairs of a DNA strand, which are able to change the protein sequence or influence the gene regulation.
In our laboratory the detection of polymorphisms occur by Real-Time PCR (Polymerase Chain Reaction). This method facilitates a exponential amplification of short DNA sequences within a longer double-stranded DNA molecule by using fluorescent probes.
Genetic analysis can be used in a big spectrum, that ranges from periodontal disease, atherosclerosis, effects of obesity, diabetes, cancer, Alzheimer's disease, osteoporosis, thrombosis to irregularities in the degradation of drugs or harmful substances and problems with detoxification of heavy metals.
Because of these multifactorial diseases are common in families, a genetic risk is clarified.
Conclusions of a genetic analysis show risk factors of dispositions to diseases in our genes, which are often only expressed in certain environmental conditions or habits.
A genetic exploration is a prevention, not only before a disease appears, but also as a specific therapy for known diseases or intolarences.
With an understanding of a disease-associated gene defect, there is an ability of unique diagnoses and therapy recommendations or rather prevention, to have an decisive advantage over a possible disease!
